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Editor-in-Chief of OBM Hepatology and Gastroenterology

Osamu Yokosuka is an Emeritus Professor of Chiba University, Japan. He graduated from Chiba University School of Medicine in 1975 then worked as a trainee under Professor K. Okuda in Chiba University Hospital till 1978. Dr. Yokosuka was a research fellow worked under Professor S. Scherlock and Professor B. H. Billing in Royal Free Hospital, London, UK from 1978 to 1980; under Professor M. Omata in Chiba University from 1980 to 1985; and under Dr. J Summers in Fox Chase Cancer Center, PA, USA in 1984. In 1985, he received a Degree of Doctor of Medical Science, and served as an Assistant Professor in Chiba University till 1994, then as Lecturer in Medicine till 2006 when he was appointed as Director and Professor of Medicine. From 2013 to 2015, he served as the Dean of Chiba University School of Medicine.

Dr. Yokosuka was the Secretary General of APASL (2008-2014). In 2016, he was elected as the President of APASL Tokyo, the President of 52nd Annual Meeting of Japan Society of Hepatology, and the President of Funabashi Central Hospital. Dr. Yokosuka’s research mainly focuses on Hepatitis and Hepatocellular Carcinoma. So far, he has published more than 700 original papers.


The Associate Editor of OBM Hepatology and Gastroenterology

Tatsuo Kanda received a medical degree in 1991 at Niigata University School of Medicine, Japan, and his PhD in 1999 at Chiba University Graduate School of Medicine, Japan. He had post-doctor training for 3 years under Prof. Ratna Ray and Prof. Ranjit Ray at Saint Louis University, St. Louis, MO, USA. In Dec. 2008, Tatsuo Kanda became a Tenure-track Associate Professor at Department of Medicine and Clinical Oncology, Chiba University, Graduate School of Medicine, Japan. In Feb. 2013, Tatsuo Kanda was nominated a permanent Associate Professor at Department of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, Japan. In 2017, Tatsuo Kanda became an Associate Professor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine. For ~25 years, he has focused his scientific interests on the topics related to liver diseases including acute liver failure, viral hepatitis and autoimmune liver diseases, and worked with Prof. Osamu Yokosuka. Tatsuo Kanda is also an expert for hepatitis A virus (HAV), HBV and HCV, and translation and replication of these viruses, and hepatocarcinogenesis. With his expertise in antiviral therapies and hepatitis virus research, Tatsuo Kanda also sees a lot of patients in clinical daily practice. Tatsuo Kanda has published more than 200 articles in peer-reviewed Journal.

Special Issue

Stem Cell Therapy

Submission Deadline: December 30, 2018 (Open)               Submit Now

Guest Editor

Luis Martinez, MD
President and CEO, Regenera Global, San Juan, 00926, Puerto Rico
E-Mail: [email protected]
Research Interests: stem cell; cancer; regenerative medicine and cell therapy; preventive medicine; clinical research

About This Topic

Dear Colleagues:

The field of stem cell medicine is advancing at a rapid pace. Interestingly, this advancement has been, to a point, fueled by parallel pathways. On one end, point of care stem cell treatments offered in clinics, and under generally lax regulatory guidelines have served to provide much empirical data on the safety and possible applications of autologous stem cell treatments. On the other end, academic institutions, alongside pharmaceutical and biotech companies, have focused on studying the complex stem cell environment. The intention being the development of stem cell biological drugs that abide by the traditional regulatory channels and which utilize placebo controlled studies to demonstrate efficacy. Independently, these pathways are, more and more, converging on a compromise between obtaining robust data, and facilitating the regulatory process. The point is to accelerate patient access to these novel therapies.

If we look at aging as a failure of stem cells, then chronic degenerative diseases arise from our bodies inability to maintain proper repair mechanisms at the cellular level. With this in mind, this special issue will focus on the translational and current clinical applications of stem cell therapies as they relate to treating, stopping, or reversing the aging process and its complications.

We invite articles that contemplate, but are not limited to the following topics:

  • Impact and modulation of telomere length on stem cell function and regenerative capacity
  • The use of stem cells to treat frailty and aging
  • Autologous vs. allogeneic stem cells for chronic degenerative diseases
  • Stem cell dosing and administration routes
  • Current approvals and coming of age indications for stem cells in medicine
  • Mitochondrial function in stem cells and aging

Planned Papers

Title: Stem cell therapy as alternative to reduce neuroinflammation
Authors: Braulio Fernandes de Carvalho, Paula Andrea Sampaio de Vasconcelos Carvalho, Ingridi de Souza Sene, Sérgio Emílio dos Santos Valente
Summary: This manuscript discusses about the use of neural stem cells and other cell types, from different sources, to fight neuroinflammation, as an alternative or alongside with drugs. Neuroinflammation is a key factor in several diseases and injuries of the nervous system.