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Biography
Biography

Editor-in-Chief of OBM Hepatology and Gastroenterology

Osamu Yokosuka is an Emeritus Professor of Chiba University, Japan. He graduated from Chiba University School of Medicine in 1975 then worked as a trainee under Professor K. Okuda in Chiba University Hospital till 1978. Dr. Yokosuka was a research fellow worked under Professor S. Scherlock and Professor B. H. Billing in Royal Free Hospital, London, UK from 1978 to 1980; under Professor M. Omata in Chiba University from 1980 to 1985; and under Dr. J Summers in Fox Chase Cancer Center, PA, USA in 1984. In 1985, he received a Degree of Doctor of Medical Science, and served as an Assistant Professor in Chiba University till 1994, then as Lecturer in Medicine till 2006 when he was appointed as Director and Professor of Medicine. From 2013 to 2015, he served as the Dean of Chiba University School of Medicine.

Dr. Yokosuka was the Secretary General of APASL (2008-2014). In 2016, he was elected as the President of APASL Tokyo, the President of 52nd Annual Meeting of Japan Society of Hepatology, and the President of Funabashi Central Hospital. Dr. Yokosuka’s research mainly focuses on Hepatitis and Hepatocellular Carcinoma. So far, he has published more than 700 original papers.

Biography

The Associate Editor of OBM Hepatology and Gastroenterology

Tatsuo Kanda received a medical degree in 1991 at Niigata University School of Medicine, Japan, and his PhD in 1999 at Chiba University Graduate School of Medicine, Japan. He had post-doctor training for 3 years under Prof. Ratna Ray and Prof. Ranjit Ray at Saint Louis University, St. Louis, MO, USA. In Dec. 2008, Tatsuo Kanda became a Tenure-track Associate Professor at Department of Medicine and Clinical Oncology, Chiba University, Graduate School of Medicine, Japan. In Feb. 2013, Tatsuo Kanda was nominated a permanent Associate Professor at Department of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, Japan. In 2017, Tatsuo Kanda became an Associate Professor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine. For ~25 years, he has focused his scientific interests on the topics related to liver diseases including acute liver failure, viral hepatitis and autoimmune liver diseases, and worked with Prof. Osamu Yokosuka. Tatsuo Kanda is also an expert for hepatitis A virus (HAV), HBV and HCV, and translation and replication of these viruses, and hepatocarcinogenesis. With his expertise in antiviral therapies and hepatitis virus research, Tatsuo Kanda also sees a lot of patients in clinical daily practice. Tatsuo Kanda has published more than 200 articles in peer-reviewed Journal.

Special Issue

Perspectives on Telomeres and Aging

Submission Deadline: January 31, 2019 (Open)                Submit Now

Guest Editor

Michael Fossel, MD, PhD
1. President of Telocyte (http://www.telocyte.com), Grand Rapids, MI 49503, USA
2. Retired Clinical Professor of Medicine, Michigan State University, Ada, MI 49301, USA
E-Mails: [email protected]; [email protected]
Website: http://www.michaelfossel.com
Research Interests: human aging; telomeres; telomerase therapy; age-related diseases; Alzheimer's disease

About This Topic

Geriatrics aims to treat the diseases of older human beings, an aim that we have consistently failed to achieve with any great efficacy. Yet both theory and growing experimental data suggest that this is about to change significantly, largely due to an increased understanding of the role played by changes in gene expression in senescent cells that result in aging disease. This is not merely a conceptual revolution, but has practical, clinical implications: we have the nascent ability to treat disease by extending telomeres and thereby resetting gene expression. The experimental results in animal studies have been remarkable and FDA human trials are planned.
Beyond the few interventional trials with telomerase activators and the planned human trials with telomerase gene therapy, there is also a growing literature on the relationship between telomere lengths and aging and, more importantly, age-related disease.
Geriatrics will publish a special issue on the relationship between telomeres and aging. We encourage submission of research on the role of telomeres (and telomerase) in geriatric medicine, to specifically include articles giving a perspective on the diagnostic and therapeutic potential of telomeres and aging.

Planned Papers

Title: Telomeres in Aging, Development, and Longevity
Author: Alvaro Macieira-Coelho

Title: Telomere, stress, stress-related mental disorders and aging
Author: Lei Zhang

Title: Telomeres and Heart failure in Aging patients
Author: Bodh I. Jugdutt
Affiliation: 2C2 W.C. Mackenzie Health Sciences Centre, Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart Institute, University of Alberta and Hospitals, 8440-112 Street, Edmonton, Alberta, Canada

Title: Telomeres, diet and ageing: what is the evidence for a link?
Authors: Anastasia Z. Kalea 1, Jessica L. Buxton 2
Affiliations:
1. UCL Division of Medicine, Rayne Building, 5 University St, London WC1E 6JF, UK;
2. School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, KT1 2EE, UK

Title: Biological age versus chronological age
Authors: Gian Andrea Rollandi 1, *, Aldo Chiesa 1, Nicoletta Sacchi 1, Matteo Puntoni 1, Adriana Amaro 2, Ulrich Pfeffer 2, *
Affiliations:
1. Ente Ospedaliera Galliera, Genova, Italy;
2. IRCCS Ospedale Policlinico San Martino, Genova, Italy;