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Editor-in-Chief of OBM Hepatology and Gastroenterology

Osamu Yokosuka is an Emeritus Professor of Chiba University, Japan. He graduated from Chiba University School of Medicine in 1975 then worked as a trainee under Professor K. Okuda in Chiba University Hospital till 1978. Dr. Yokosuka was a research fellow worked under Professor S. Scherlock and Professor B. H. Billing in Royal Free Hospital, London, UK from 1978 to 1980; under Professor M. Omata in Chiba University from 1980 to 1985; and under Dr. J Summers in Fox Chase Cancer Center, PA, USA in 1984. In 1985, he received a Degree of Doctor of Medical Science, and served as an Assistant Professor in Chiba University till 1994, then as Lecturer in Medicine till 2006 when he was appointed as Director and Professor of Medicine. From 2013 to 2015, he served as the Dean of Chiba University School of Medicine.

Dr. Yokosuka was the Secretary General of APASL (2008-2014). In 2016, he was elected as the President of APASL Tokyo, the President of 52nd Annual Meeting of Japan Society of Hepatology, and the President of Funabashi Central Hospital. Dr. Yokosuka’s research mainly focuses on Hepatitis and Hepatocellular Carcinoma. So far, he has published more than 700 original papers.


The Associate Editor of OBM Hepatology and Gastroenterology

Tatsuo Kanda received a medical degree in 1991 at Niigata University School of Medicine, Japan, and his PhD in 1999 at Chiba University Graduate School of Medicine, Japan. He had post-doctor training for 3 years under Prof. Ratna Ray and Prof. Ranjit Ray at Saint Louis University, St. Louis, MO, USA. In Dec. 2008, Tatsuo Kanda became a Tenure-track Associate Professor at Department of Medicine and Clinical Oncology, Chiba University, Graduate School of Medicine, Japan. In Feb. 2013, Tatsuo Kanda was nominated a permanent Associate Professor at Department of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, Japan. In 2017, Tatsuo Kanda became an Associate Professor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine. For ~25 years, he has focused his scientific interests on the topics related to liver diseases including acute liver failure, viral hepatitis and autoimmune liver diseases, and worked with Prof. Osamu Yokosuka. Tatsuo Kanda is also an expert for hepatitis A virus (HAV), HBV and HCV, and translation and replication of these viruses, and hepatocarcinogenesis. With his expertise in antiviral therapies and hepatitis virus research, Tatsuo Kanda also sees a lot of patients in clinical daily practice. Tatsuo Kanda has published more than 200 articles in peer-reviewed Journal.

Special Issue

Genetic Testing

Submission Deadline: April 1, 2019 (Open)                Submit Now

Guest Editor

Joep Geraedts, PhD
Emeritus Professor of Genetics and Cell Biology, Maastricht University, P.O. Box 616, 6200 MD Maastricht, the Netherlands
E-Mails: [email protected]; [email protected]
Research Interests: reproductive genetics; cancer genetics; preimplantation genetic diagnosis; genetic testing; evolution, etc

About This Topic

The special issue genetic testing will cover a broad range of activities, which can be divided in the following types of testing: genealogical, forensic and medical. Furthermore, genetic testing is done in both humans and animals. In this special issue attention will be paid to the methods used. Finally, also the ethical and legal aspects will be covered.
Genealogical testing is done to determine ancestral ethnicity and relationships. Many companies are offering these tests. Based on a saliva sample ancestral information, including Neanderthal ancestry is reported.
Forensic DNA testing in humans can be applied among others to test suspects of crime but also for identification purposes of missing persons, crime victims or in case of adoption. Y chromosomal haplotyping is employed in paternity disputes.
In wildlife forensic testing is used to determine illegal trade in protected and endangered species or to trace the geographic origin or the species of a sample.
Medical genetic testing is done before, during and after pregnancy to identify chromosomal mutations and single gene disorders. Testing can be done for screening, diagnosis, and prognosis of diseases consistent with a genetic cause and to guide drug therapy to improve drug efficacy and avoid adverse effects (pharmacogenomics).
All medical genetic testing should be voluntary. Therefore, this special issue will devote attention to risks, complications and counselling aspects as well.

Planned Papers

Title: Fetal dysmorphology in the Genomic Era – A practical approach.
Author: Margaret Evans

Title: A multifactorial test for predisposition to melanoma integrating genetic and clinical risk factors in daily clinical practice
Authors: Meriem Benfodda, Steven Gazal, Vincent Descamps, Nika Madjlessi, Celeste Lebbe, Nicole Basset-Seguin, Alain Archimbaud, Kristina Opletalova, Valerie Vuong, Caroline Nicaise ergere, Sandrine Massart-Manil, Bruno Machuel, Anne Grange, Philippe Saiag, Nicolas Dupin, Pierre Wolkenstein, Armand Bensussan, Eduardo Nagore, Rajiv Kumar, Florent Grange, Nadem Soufir

Title: Preimplantation Genetic Testing for HLA-matching: an overview of clinical application and utility
Authors: Georgia Kakourou, Thalia Mama, Christina Vrettou, Jan Traeger-Synodinos

Title: Genetic testing of infertility
Author: Joep Geraedts

Title: Carrier Screening Testing
Authors: Carles Giménez, Montserrat Palahí, Estefania Toro, Marta Sánchez, Diana Campos, Elena Garcia, Mireia Sandalinas