Open Access Review

Paradigms in Integrative Medicine and the Place of Clinical Hypnosis

Donald Moss
Received: January 20, 2020; Published: February 19, 2020; doi:10.21926/obm.icm.2001007

Abstract: The face of illness has changed with progress in public health, immunizations, and antibiotic medication. Today, medical clinics are more likely to see patients with chronic illnesses, stress-related conditions, and complex bio-psycho-social conditions. This is a global trend, affecting patients wor [...]

Open Access Original Research

Exploring the Effects of Aerobic Exercise on Blood Coagulability in Caregivers of Patients with Dementia: A Randomized Controlled Trial

Akemi Hirano, Yusuke Suzuki, Hiroyuki Umegaki, Toshio Hayashi, Koichiro Ina, Joji Onishi, Jun Hasegawa, Masafumi Kuzuya
Received: October 13, 2019; Published: February 19, 2020; doi:10.21926/obm.geriatr.2001108

Abstract: The incidence of vascular diseases among caregivers of dementia patients is high, and one potential cause is the exacerbation of blood coagulability due to mental strain from caregiving. This study aimed to examine the effects of aerobic exercise on blood coagulability, from the perspective of impro [...]

Open Access Short Review

Alzheimer's Disease: Parsing the Pathways Leading to the Disease Based on the Spirochete/Biofilm Hypothesis

Herbert B. Allen
Received: December 31, 2019; Published: February 19, 2020; doi:10.21926/obm.geriatr.2001107

Abstract: A pathway which highlighted spirochetes (Borrelia burgdorferi and dental treponemes) that made biofilms which led to Alzheimer’s disease has recently been promulgated. All the Alzheimer’s disease, on which this pathway was based, had been specifically confirmed both clinically and pathologically. Th [...]

Open Access Review

Hematopoietic Stem Cell Transplantation in Refractory Celiac Disease: An Overview with Focus on Infectious Complications

Abdulbaqi Al-Toma, Harry R. Koene
Received: December 16, 2019; Published: February 18, 2020; doi:10.21926/obm.transplant.2001101

Abstract: Refractory celiac disease (RCD) is a rare condition in which a known celiac patient, usually an adult, suffers from persistence or recurrence of gluten-related symptomatology, laboratory abnormalities, and inflammatory enteropathy despite following an optimal dietary therapy with gluten-free diet (G [...]

Open Access Review

Informatics and Artificial Intelligence Approaches that Promote Use of Integrative Health Therapies in Nursing Practice: A Scoping Review

Sheng-Chieh Lu, Connie W. Delaney, Mary Fran Tracy, Chih-Lin Chi, Karen A. Monsen
Received: December 30, 2019; Published: February 17, 2020; doi:10.21926/obm.icm.2001006

Abstract: Integrative health (IH) therapies are increasingly used to manage health conditions, but barriers hindering nurses from offering IH therapies persist. Informatics and artificial intelligence (AI) approaches have potential to promote nurses’ professional use of IH therapies. The purposes [...]

Open Access Review

Problems Associated with the Measurement of Neuropsychiatric Symptoms of Dementia

Natalie G. Regier
Received: December 04, 2019; Published: February 17, 2020; doi:10.21926/obm.geriatr.2001106

Abstract: Neuropsychiatric symptoms (NPS) affect nearly all persons living with dementia (PLWD) at some point during the course of the disease. Given the absence of a cure or effective pharmacotherapy for dementia, it is particularly important to prevent, measure, track, and manage NPS in dementia care. Unfor [...]

Open Access Review

Cortical Activity and Rhythmic Patterns in Mouse Models of Aging and Alzheimer’s Disease

Marcel Ruiz-Mejias, Patricia Castano-Prat, Tony Donegan, Maria V. Sanchez-Vives
Received: December 31, 2019; Published: February 14, 2020; doi:10.21926/obm.geriatr.2001105

Abstract: Aging and Alzheimer’s disease (AD) have been reported to induce changes in the cerebral cortex circuits. The present review aims to study these alterations by reviewing emergent cortical activity with a focus on the rhythmic patterns. The rationale for this approach was two-fold: (i) eme [...]

Open Access Editorial

Transplantation of a Kidney with an Extra-Renal Organ

Steven R. Potter
Received: February 10, 2020; Published: February 13, 2020; doi:10.21926/obm.transplant.2001100

Open Access Original Research

Zero-Emission Geothermal Power Generation: Experimental Study on Carbonate Mineralization through CO2-Andesitic Pyroclastic Rock Interaction at Oku-Aizu Geothermal Plant

Ryosuke Oochi, Kengo Aoyama, Akira Ueda
Received: November 27, 2019; Published: February 12, 2020; doi:10.21926/jept.2001002

Abstract: In order to achieve advancement in zero-emission geothermal power generation for fixing the CO2 in the geothermal fluids to the carbonate minerals after binary power generation and reinjection of the fluid into the reservoir, batch-type experiments and geochemical [...]

Open Access Original Research

Eplet-Based HLA Class II Matching for Transplantation: Design of a Repertoire of Interlocus Eplets Shared between HLA-DR, -DQ and -DP Alleles

Rene J. Duquesnoy, Marilyn Marrari
Received: December 13, 2019; Published: February 11, 2020; doi:10.21926/obm.transplant.2001099

Abstract: Many studies have demonstrated that HLA-DR, HLA-DQ and HLA-DP matching at the eplet level reduces allograft rejection and improves transplant outcome. Such studies have examined the eplet effect for the individual class II loci, but until now little attention has been given to so-called interlocus c [...]

Open Access Review

Behaviors of Persons with Dementia: A Review and New Perspective for Future Research

Morgan J. Minyo, Katherine S. Judge
Received: July 30, 2019; Published: February 07, 2020; doi:10.21926/obm.geriatr.2001104

Abstract: Through the assessment of previous and current literature on the behaviors experienced by persons with dementia, this review discusses the terminology, conceptual models, measurement techniques, and non-pharmacological interventions employed within behavioral research. Additionally, this review cons [...]

Open Access Review

Hypnosis for Clinical Pain Management: A Scoping Review of Systematic Reviews

Anupa Pathak, Saurab Sharma, Mark P. Jensen
Received: December 30, 2019; Published: February 5, 2020; doi:10.21926/obm.icm.2001005

Abstract: There is a growing body of research evaluating the effects of hypnosis for the management of clinical pain. A summary of the recent systematic review would help understand the quality of evidence regarding the efficacy of hypnosis, and provide directions for future research. We conducted a scoping r [...]

Open Access Review

Utility of Fungal Cell Markers in Pediatric Bone Marrow Transplant Recipients for Screening and Diagnosis of Invasive Fungal Infections

Nour Hasan, Ankita P. Desai, Jignesh Dalal
Received: November 12, 2019; Published: February 03, 2020; doi:10.21926/obm.transplant.2001098

Abstract: Invasive fungal disease (IFD) is a significant contributor to morbidity and mortality in pediatric patients undergoing hematopoietic stem cell transplantation (HSCT). Early detection and timely initiation of antifungal therapy is important for improved outcome, but diagnosis remains difficult, espec [...]

Open Access Perspective

Target Tau, not Amyloid, to Prevent and Treat Alzheimer’s Disease

Margaret M Esiri
Received: November 17, 2019; Published: February 04, 2020; doi:10.21926/obm.geriatr.2001103

Abstract: In this article I wish to put the case for a change of emphasis in the approach to finding a prevention/treatment for Alzheimer’s disease from a focus on beta amyloid to one on tau. In particular, I make the case for aiming to prevent the spread of abnormal tau from the medial temporal lobe to wides [...]

Open Access Editorial

Immunosuppression in Kidney Transplantation

Maurizio Salvadori, Aris Tsalouchos
Received: January 19, 2020; Published: February 03, 2020; doi:10.21926/obm.transplant.2001097

Abstract: Immunosuppressive therapy in renal transplantation is divided into two phases as induction and maintenance therapy. Induction therapy is an intense immunosuppressive therapy administered at the time of kidney transplantation to reduce the risk of acute allograft rejection. In general, induction immu [...]

Open Access Case Report

Dual Kidney Transplantation after Hypothermic Oxygenated Perfusion from Marginal Donor after Circulatory Death with Acute Kidney Injury: A Case Report

Federica Odaldi, Vanessa De Pace, Giacomo Frascaroli, Giuliana Germinario, Giorgia Comai, Francesco Vasuri, Gaetano La Manna, Matteo Ravaioli
Received: November 22, 2019; Published: February 03, 2020; doi:10.21926/obm.transplant.2001096

Abstract: Donation after circulatory death (DCD) is an increasingly used resource to alleviate chronic renal graft shortages. Organs from donors with progressively increased creatinine levels due to acute kidney injury are used, but the effects of this condition on kidney transplantation are still unclear. Ex [...]

Open Access Original Research

An Estimate of Possible Impacts of Superoxide Chemistry on Seawater pH: A Mapping Exercise

Marco Minella, Khan M. G. Mostofa, Cong-Qiang Liu, Davide Vione
Received: September 5, 2019; Published: January 21, 2020; doi:10.21926/obm.acr.2001004

Abstract: Superoxide, produced photochemically as well as microbially, is an important reactant present in seawater and a major source of hydrogen peroxide. Superoxide decay may occur through catalyzed or uncatalyzed dismutation forming H2O2 and O2, through oxidation to O2, or through reduction into H2O2. Und [...]

Open Access Original Research

Views of Conventional Medicine and Integrative Medicine among Informal Dementia Caregivers and Healthcare Professionals in NW England

Garuth Eliot Chalfont, Jane Simpson, Fiona J R Eccles, Christine Milligan
Received: September 06, 2019; Published: January 21, 2020; doi:10.21926/obm.geriatr.2001102

Abstract: The urgent need for innovative approaches to dementia treatment that are acceptable, effective and affordable underlies this research. Growing evidence supports ‘integrative medicine’ as a potential treatment approach aligned with and including conventional medicine. However, success will depend on [...]

Open Access Review

Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options

Kim Lawson
Received: November 05, 2019; Published: January 20, 2020; doi:10.21926/obm.neurobiol.2001049

Abstract: Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis. Heterogeneity of clinical expression of fibromyalgia with a [...]

Open Access Book Review

Review of: Forgotten: Narratives of Age-Related Dementia and Alzheimer’s Disease in Canada. By Marlene Goldman. McGill-Queen’s Press, 2017

Julia Henderson
Received: November 05, 2019; Published: January 17, 2020; doi:10.21926/obm.geriatr.2001101

Abstract: none

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Recent Progress in Materials

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Advances in Environmental and Engineering Research

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Guest Editor: Yuri Shavrukov

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